How can I measure the fluid flow in microfluidic channel?
1
Hello MEMS community,
I want to measure the fluid flow velocity inside microfluidic channel. Is there any standard measurements equipment that I can use?
Any help will be much appreciated.
Thanks
Mario
I want to measure the fluid flow velocity inside microfluidic channel. Is there any standard measurements equipment that I can use?
Any help will be much appreciated.
Thanks
Mario
2
Hello Marino,
to the best of my knowledge, I don't know if there is any standard or commercial setup you can use to measure your fluid flow velocity. Most of research groups in microfluidic field use their own home-made setup. Usually this setup consists of:
1. A microscopic objective,
2. Light/laser source
3. Tracking particles ( fluorescence, latex beads, ...)
4. Camera
5 Video recorder,
6. Particle image velocimetry (PIV) software.
a configuration of similar setup can be found on many text-books, similar setups can be found on this text book "AC Electrokinetic: Colloids and Nanoparticles"
to the best of my knowledge, I don't know if there is any standard or commercial setup you can use to measure your fluid flow velocity. Most of research groups in microfluidic field use their own home-made setup. Usually this setup consists of:
1. A microscopic objective,
2. Light/laser source
3. Tracking particles ( fluorescence, latex beads, ...)
4. Camera
5 Video recorder,
6. Particle image velocimetry (PIV) software.
a configuration of similar setup can be found on many text-books, similar setups can be found on this text book "AC Electrokinetic: Colloids and Nanoparticles"
3
Hello,
there are different techniques you can use for the measurements of fluid velocity. Some of them are more exotic, such as the X-ray and the Optical doppler tomography velocity imaging. The PIV and the Fluorescence Correlation Spectroscopy are the most common methods. The second one is perfect if you can inject a fluorescent tracer in your microchannels and it permits the determination of the velocity with high spatial resolution and high sensitivity at low concentrations. You can find some details in: Gosch, M., Blom, H. H.; Heino, T.; Rigler, R. Anal. Chem. 2000, 72, 3260-3265; Brister, P. C., Kuricheti, K. K., Buschmann, V.; Weston, K. D. Lab on a Chip 2005, 5, 785-791.
Ilaria
there are different techniques you can use for the measurements of fluid velocity. Some of them are more exotic, such as the X-ray and the Optical doppler tomography velocity imaging. The PIV and the Fluorescence Correlation Spectroscopy are the most common methods. The second one is perfect if you can inject a fluorescent tracer in your microchannels and it permits the determination of the velocity with high spatial resolution and high sensitivity at low concentrations. You can find some details in: Gosch, M., Blom, H. H.; Heino, T.; Rigler, R. Anal. Chem. 2000, 72, 3260-3265; Brister, P. C., Kuricheti, K. K., Buschmann, V.; Weston, K. D. Lab on a Chip 2005, 5, 785-791.
Ilaria
